How to Diagnose Chagas Disease: Tests and Procedures

Categories: HEALTH

Content Image

Chagas disease is diagnosed by looking for antibodies against the parasite in the chronic phase and by looking for the parasite itself during the acute phase.


Tests during the acute phase (first few weeks to months of infection):


Microscopic analysis of blood: The Trypanosoma cruzi parasite can be directly seen in the bloodstream using a blood smear, which is a quick and reasonably priced test. When parasite levels are high in the initial weeks following infection, this test works well.


Tests during the chronic phase (years to decades after infection):


a. Serologic tests (ELISA):   The primary method for identifying chronic Chagas disease is blood testing. They identify antibodies that the T. cruzi parasite has caused your body to manufacture. There are several serologic tests available, the most popular of which is the enzyme-linked immunosorbent assay (ELISA). Further testing may be necessary, though, as a positive test does not always imply an ongoing infection—it merely signals exposure to the parasite. Two varieties of serologic tests exist:


IFA (indirect fluorescent antibody): This test is highly specific but less sensitive than ELISA.


IFI (indirect fluorescent antibody): This test is more sensitive than IFA but less specific.


b. Parasitologic tests:   Though less frequently employed, these tests can be useful in verifying a diagnosis, particularly in those who’s serologic testing come up negative. Among them are:


c. Xenodiagnosis: In this procedure, an infected person's blood is used to feed kissing bugs that were produced in a lab. After a month, the intestines of the bugs are checked for parasites. This is a laborious test that is not easily accessible.


d. Hemoculture: This test attempts to grow the T. cruzi parasite from a patient's blood in a laboratory setting. It is also not widely available and has low sensitivity.


Other diagnostic tests:


Once chronic Chagas disease is confirmed, your doctor may recommend additional tests to assess potential damage to your heart, esophagus, or intestines. These tests may include:


a. Electrocardiogram (ECG): This test measures the electrical activity of your heart and can detect abnormal heart rhythms or damage to the heart muscle.


b. Echocardiogram: This test uses ultrasound waves to create images of your heart, allowing your doctor to assess the structure and function of your heart valves and chambers.


c. X-ray or CT scan of the chest or esophagus: These imaging tests can help identify enlargement of the esophagus (megaesophagus) or colon (megacolon).

Top articles
Should we compulsorily make time for yoga Published at:- What is peripheral artery disease (PAD) and how does it affect our body Published at:- Best Exercises to Reduce Pain Due to Peripheral Arterial Disease Published at:- Sharp Pain In Cervix During Period Published at:- Sharp pain in cervix not pregnant Published at:- Fibromyalgia nerve pain medication Published at:- Deep penetration causing cramps and bleeding Published at:- Fibromyalgia Symptoms In Females Treatment Published at:- Cervix pain during ovulation Published at:- Cervical pain during early pregnancy Published at:- Japanese healthy lifestyle habits Published at:- International menstrual hygiene day Published at:- Vitamin B deficiency diseases list Published at:- Graphic Eyeliner Hooded Eyes Published at:- Right Side of Neck and Shoulder Pain Published at:- Cat Bite Infection Treatment Published at:- What Is a Dangerously High Bun Creatinine Ratio Published at:- What Is a Dangerously Low Potassium Level Published at:- What Are the Dangers of High Potassium Published at:- Which Is More Dangerous Hepatitis A or B Published at:- Which Hepatitis Is Most Dangerous in Pregnancy Published at:- Pregnancy Workouts First Trimester Published at:- Pregnancy Workout 2nd Trimester Published at:- Easy Evening Snacks Recipe Published at:- Early Stage Diabetes Eyes Symptoms Published at:- Wrong Sleeping Positions during Pregnancy Published at:- Sitting Positions to Avoid during Pregnancy Published at:- PCOS Awareness Month 2023 Published at:- Natural Remedies for Psoriasis Published at:- Understanding Cervical Dystonia: Unraveling the Mystery of a Complex Disease Published at:- Streptococcus Pneumonia Bacteria Published at:- Navigating the Storm: Dealing with a Head Cold Accompanied by Fever Published at:- Understanding and Managing Upper Respiratory Cold: A Comprehensive Guide Published at:- Combating the Winter Cold: Comprehending and Handling Extended Coughs during the Chilly Season Published at:- Herbal Tea for Winter Detox: Cleansing Your Body in the Cold Months Published at:- Best Herbal Teas for Boosting Your Immune System in Winter Published at:- Combatting Cracked Heels: Essential Winter Foot Care Strategies Published at:- 5 Soothing Herbal Tea Blends to Warm You Up This Winter Published at:- HIV Antibody Test Published at:- HIV RNA test Published at:- Unraveling the Effectiveness of HIV Antigen Tests Published at:- World AIDS Day 2023: Examining Advances and Agreeing to Promote Better Health in the Future Published at:- Supporting Loved Ones with HIV: Practical Tips and Emotional Guidance Published at:- GBS Disease in Adults: Risk Factors, Complications and Management Published at:- Understanding and Implementing Effective Piles Self-Treatment Strategies Published at:- How Loneliness Rewires Our Brain: From Perception to Connection Published at:- JN.1: The Latest Developments in the Corona Variant Landscape Published at:- What Causes Stroke: Understanding the Disruption in Blood Flow to the Brain Published at:- Kids and Screens: Preventing Mobile Addiction in Children Published at:- Chaitra Navratri Fasting Made Easy: Practical Tips to Follow Published at:- How to Diagnose Chagas Disease: Tests and Procedures Published at:- 10 Effective Strategies to Improve Memory Recall Published at:-