PEBC (Clinical Sciences) Sample Questions
Categories: PEBC Canada
Ques. At typical dosing, which of the following antidepressant medications is associated with the highest incidence of nausea?
a. Sertraline
b. Fluoxetine
c. Duloxetine
d. Escitalopram
e. Desvenlafaxine
Ques. Which of the following statements is correct regarding the use of fluoroquinolones?
a. Fluoroquinolones can cause blood glucose alterations in elderly patients who take oral antihyperglycemic medications.
b. Healthy women with acute uncomplicated cystitis should be treated for a minimum of 7 days with a fluoroquinolone.
c. Therapeutic drug monitoring is recommended with prolonged fluoroquinolone therapy, to avoid ototoxicity.
d. In the case of treatment failure, another fluoroquinolone should be tried before switching to a different antibiotic class.
e. All fluoroquinolones have equal efficacy when used to treat patients with community-acquired pneumonia.
Ques. Which of the following medications requires monitoring for the adverse effect of dyslipidemia?
a. Ciprofloxacin
b. Allopurinol
c. Isotretinoin
d. Ramipril
e. Raloxifene
Ques. The mother of a 6 year old child presents to the pharmacist with a written prescription for amoxicillin that was ordered by the physician three days earlier. She states that her child was diagnosed wit otitis media and the symptoms have remained the same over the past three days.
Which of the following is the most appropriate pharmacist response?
a. Fill the prescription as written
b. Refuse to fill the prescription as the antibiotic order is no longer current
c. Indicate a need to contact the prescriber before filling the prescription at this time
d. Fill the prescription for a quantity that is the ordered amount less three days' supply
e. Explain that, at this late date, antibiotic therapy will likely be ineffective for the child
Ques. RF is an 80 year old female who developed CDAD (Clostridium difficile-associated diarrhea) after recent treatment of a urinary tract infection with ciprofloxacin. She is admitted to hospital with profound diarrhea (eight watery bowel movements per day) and fever (39.5° C). Based on her symptoms, which of the following is the most appropriate therapy choice for her?
a. Oral metronidazole
b. Intravenous metronidazole
c. Oral cholestyramine
d. Oral vancomycin
e. Intravenous vancomycin
Ques. CC, a 72 year old female, complains to the pharmacist that her stomach has been bothering her recently. Current medications include: levothyroxine 100 mcg po daily (x 30 years), acetaminophen 500 mg po gid (x 5 months), atorvastatin 40 mg po at bedtime (x 4 years), ibuprofen 400 mg po tid prn joint pain (x 2 months), and zopiclone 3.75 mg po at bedtime prn (x 3 months). Based on CC's current symptoms, which of the following drug therapy problems best describes CC's current situation?
a. Too high a dosage of atorvastatin
b. Too high a dosage of zopiclone
c. Need for cytoprotection with ibuprofen
d. Drug interaction between atorvastatin and zopiclone
e. Too low a dosage of levothyroxine
Ques. A 27 year old patient presents to a community pharmacy for the first time and tells the pharmacist that he experienced an allergy to a penicillin product as a child. His symptoms included hives, wheezing and facial swelling, which resulted in hospitalized care. Which of the following is the most important reason for a community pharmacist to document this type of information in a patient's medication profile record?
a. To provide drug allergy information to the patient's insurance provider.
b. To encourage the patient to fill future prescriptions at this pharmacy.
c. To advertise relevant pharmacy products or services to appropriate patients.
d. To enhance continuity of patient care regardless of the prescriber.
e. To provide a record of cognitive services for insurance reimbursement.
IN THESE QUESTIONS INCLUSIVE REFER TO THE FOLLOWING:
SM is a 34 year old female who, while vacationing in Mexico, began prophylactic treatment for travellers' diarrhea. Shortly thereafter she complained of a feeling of fullness in her ears, black stools and a black tongue. SM's previous history includes an allergy to sulfonamides.
Ques. Which of the following drugs could be the cause of SM's complaints?
a. Bismuth subsalicylate
b. Cotrimoxazole (sulfamethoxazole/trimethoprim)
c. Doxycycline
d. Amoxicillin
e. Loperamide
Ques. An organism commonly implicated in the cause of travellers' diarrhea is:
a. Bacteroides fragilis.
b. Escherichia coli.
c. Clostridium difficile.
d. Listeria monocytogenes.
e. Pseudomonas aeruginosa.