PEBC (Product Distribution) Sample Questions

14 October, 2022

Categories: PEBC Canada

Ques. A physician asks the pharmacist about obtaining a Special Access Programme (SAP) medication. Which of the following statements is correct regarding accessing medications through SAP?

a. SAP authorization certifies that the drug is safe and effective.

b. All SAP medications are provided free of charge to patients.

c. Medications may be authorized for a maximum duration of three months.

d. The manufacturer has the final authority on whether to supply the requested drug.

Ques. Which of the following classes of medications is most likely to be administered by the intravenous piggyback method?

a. Antibiotics

b. Opioids

c. Insulins

d. Erythropoiesis regulating hormones

Ques. Which of the following statements is correct regarding compounded sterile preparations (CSPs) in a hospital pharmacy?

a. Immediate-use CSPs that are intended for urgent use situations have less stringent preparation criteria than other CSPs.

b. A multi-dose batch of an immediate-use CSP may be prepared for a patient.

c. A pharmacist must be directly responsible for the labelling of all finished CSPs, even when prepared by trained personnel.

d. Beyond-use dates are ideally determined by test sampling of the individual CSP batch.

Ques. Which of the following drug orders is incomplete and requires follow-up with the prescriber?

a. Zithromax Z-Pak® (azithromycin 250 mg), 2 tabs po day 1 and 1 tab po days 2 to 5

b. Flonase® (fluticasone) 100 mcg spray, 1 or 2 sprays in each nostril bid x 1 bottle

c. Actonelo® (risedronate), 35 mg po once weekly x 12 tabs

d. Zocor® (simvastatin), 1 tab po hs for 3 months

Ques. Which of the following factors is most likely to contribute to a widespread shortage of a pharmaceutical product?

a. Lot recall

b. Patent expiration

c. De-listing by provincial drug plans

d. Lack of raw material

Ques. Which of the following characteristics is the most important for assessing the bioequivalence of two brands of a pharmaceutical dosage form?

a. Excipients

b. Physical appearance

c. Manufacturing cost

d. Pharmacokinetic properties

Ques. Which of the following injectable products requires refrigerated storage?

a. Gravol® (dimenhydrinate)

b. Enbrel® (etanercept)

c. Imitrex® (sumatriptan succinate)

d. EpiPen® (epinephrine)

Ques. A male patient weighing 165 pounds is brought to the Emergency Room approximately six hours after ingestion of an overdose of acetaminophen. Acetylcysteine IV will be administered according to the following dosing regimen:

Total IV dose = 300 mg/kg given over 20 hours, as follows:

Loading Dose: 150 mg/kg in 250 mL D5W IV given over 15 minutes, followed by:

First infusion: 50 mg/kg in 500 mL D5W IV given over 4 hours, followed by:

Second infusion: 100 mg/kg in 1 L D5W given over 16 hours.

Which of the following represents the correct preparation of the three acetylcysteine IV bags needed for this patient?

a. Acetylcysteine 2.25 g in 250 mL D5W; 0.2 g in 500 mL D5W; 1.6 g in 1 L D5W

b. Acetylcysteine 11.25 g in 250 mL D5W; 3.75 g in 500 mL D5W; 7.5 g in 1 L D5W

c. Acetylcysteine 22.5 g in 1 L of D5W

d. Acetylcysteine 24.75 g in 250 mL D5W; 8.25 g in 500 mL D5W; 16.5 g in 1 L D5W

Ques. A patient is receiving warfarin (using 2 mg tablets in compliance packaging) according to the following regimen:

Sunday (Su), Tuesday (Tu), Thursday (Th) and Friday (F) - 6 mg

Monday (M), Wednesday (W) and Saturday (Sa) - 2 mg

The patient's recent INR results have been consistently high and it is decided that the weekly dose should be reduced by 20%. Which of the following regimens would be most appropriate if the patient is to continue using 2 mg tablets in compliance packaging?

a. Su, Tu, F-5 mg; M, Th - 3 mg; W, Sa - 1 mg

b. Su, M, Tu, W, Th, F-4 mg; Sa - no warfarin

c. 4 mg daily

d. 3.5 mg daily

Ques. JK is a 68 year old female with type 2 diabetes. Her current medications include:

Perindopril 4 mg po daily

Rosuvastatin 20 mg po at bedtime

Metformin 1000 mg po bid

Sitagliptin 100 mg po daily

Risedronate 35 mg po once weekly on Wednesdays

Vitamin D 1000 units po daily

The pharmacist notices that JK is non-adherent with her medications, as she requests refills at inappropriate frequencies. JK explains that she sometimes forgets to take her medications since there are so many and she doesn't feel any difference from missing some of them. She often babysits her young grandchildren. The pharmacist offers to prepare JK's medications in compliance packaging. What is the most valid reason for offering this service to JK? Compliance packaging:

a. is warranted due to JK's advanced age.

b. will ensure that JK is adherent to her medications.

c. is warranted due to JK's possible cognitive impairment.

d. will ensure that JK's grandchildren cannot access her medications.

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