PEBC (Psychiatric and Neurological Drugs) Sample Questions Set-2
Categories: PEBC Canada
Ques. A patient has been taking an opioid analgesic for the past three months for back pain resulting from a workplace injury. All of the following behaviors could be indicators of a developing addiction disorder, EXCEPT:
a) incidents of lost prescriptions.
b) frequent requests for early refills.
c) prescriptions from multiple family physicians.
d) patient concerns regarding side effects.
e) patient concerns regarding lack of efficacy.
Answer: (d)
In these questions inclusive refer to the following:
FG is a 65-year-old war veteran with a 40-year history of paranoid schizophrenia. His symptoms include poor personal hygiene, blunted affect, and delusions, accompanied by auditory and visual hallucinations. His delusional symptoms relate to his wartime experiences. His visual hallucinations involve enemy soldiers from the war who he believes are stalking him. FG's auditory hallucinations include the sounds of war, accompanied by enemy soldiers threatening to end his life if he does not keep his guard up. FG has been unable to maintain a job or adequate housing for many years. He currently lives under a bridge “in case he needs to make a getaway down the river.” When workers from the free clinic are able to locate him, they attempt to provide medical care and evaluate his schizophrenia. If sample medications are available, they provide him with them. According to their records, FG was given haloperidol 15 mg 3 times daily and benztropine 1 mg 3 times daily when they last evaluated him. He was given enough medication for a few weeks so that they could evaluate the effectiveness and any adverse effects. During previous trials with other neuroleptic agents, extrapyramidal side effects have limited the dose FG could tolerate. The physician on the team would like to discontinue the haloperidol and initiate an agent with fewer extrapyramidal side effects. He searches the medication supply and finds that he has samples of olanzapine, quetiapine, aripiprazole, and risperidone, ziprasidone
Ques. Which agent is least likely to cause extra pyramidal side effects?
A) olanzapine
B) quetiapine
C) Aripaprazole
D) Risperidone
E) ziprasidone
Answer: (b)
Ques. Which agent is most likely to cause QT prolongation side effects?
A) olanzapine
B) quetiapine
C) Aripaprazole
D) Risperidone
E) ziprasidone
Answer: (e)
Ques. Which agent causes the highest weight gain side effects?
A) olanzapine
B) quetiapine
C) Aripaprazole
D) Risperidone
E) ziprasidone
Answer: (a)
Ques. MP was recently diagnosed with schizophrenia and was just discharged from hospital. He is currently taking risperidone 3 mg twice daily. He tells you that he no longer has delusions or hallucinations and is feeling more motivated, but he’s been having trouble with symptoms that he describes as “wanting to crawl out of his skin” and a hand tremor. What is appropriate reasoning to tell an MP?
I) the symptoms he is describing are normal side effects of risperidone; because his symptoms of schizophrenia are well controlled, there is nothing that can be done
II) sometimes the risperidone can cause the symptoms he is describing; with his permission, you will call his psychiatrist to discuss reducing his dosage
III) sometimes the risperidone can cause the symptoms he is describing; with his permission, you will call his psychiatrist to discuss switching risperidone with clozapine because it is associated with fewer extrapyramidal symptoms
Ques. What receptor likely has the largest impact on risk of sedation?
a) histamine H1 receptors
b) dopamine D2 receptors
c) histamine H2 receptors
d) alpha-1 receptors
e) alpha 2 receptors
Answer: (a)
Ques.Which agent must be taken with meals?
A) olanzapine
B) quetiapine
C) Aripaprazole
D) Risperidone
E) ziprasidone
Answer: (e)
Ques. Which agent is NOT approved for bipolar disorder?
A) olanzapine
B) quetiapine
C) Aripaprazole
D) Risperidone
E) ziprasidone
Answer: (e)