PEBC (Cardiovascular and CNS) Sample Questions

21 October, 2022

Categories: PEBC Canada

Ques. MP was recently diagnosed with schizophrenia and was just discharged from hospital. He is currently taking risperidone 3 mg twice daily. He tells you that he no longer has delusions or hallucinations and is feeling more motivated, but he’s been having trouble with symptoms that he describes as “wanting to crawl out of his skin” and a hand tremor. What is appropriate reasoning to tell an MP?

I) the symptoms he is describing are normal side effects of risperidone; because his symptoms of schizophrenia are well controlled, there is nothing that can be done

II) sometimes the risperidone can cause the symptoms he is describing; with his permission, you will call his psychiatrist to discuss reducing his dosage.

III) sometimes the risperidone can cause the symptoms he is describing; with his permission, you will call his psychiatrist to discuss switching risperidone with clozapine because it is associated with fewer extra pyramidal symptoms.

A) I only

B) III only

C) I and II

D) II and III

E) I, II, III

Answer: (d)

Ques. What receptor likely has the largest impact on risk of sedation?

a) histamine H1 receptors

b) dopamine D2 receptors

c) histamine H2 receptors

d) alpha1 receptors

e) alpha 2 receptors

Answer: (a)

Ques. Which agent must be taken with meals?

A) olanzapine

B) quetiapine

C) Aripaprazole

D) Risperidone

E) ziprasidone

Answer: (e)

Ques. What is not monitored for risperidone?

A) blood pressure and pulse on dose titration

B) Body mass index (BMI)

C) Liver function test at baseline and Q6m

D) Lipids and triglyceride levels

E) Cardiomyopathy like chest pain

Answer: (e)

Ques. After starting antipsychotics therapy. When symptoms of schizophrenia will start to resolve?

A) 2 weeks

B) 4 weeks

C) 6 weeks

D) 8 weeks

E) one month

Answer: (a)

Ques. The doctor prescribes a combination treatment of SSRI+benzodiazepines for which there is a risk for a pharmacokinetic interaction. Which of the following is the best course of action?

A) Recommend avoiding the combination due to the narrow safety margin of SSRI

B) Recommend avoiding the combination due to narrow safety of margin of benzodiazepines

C) Dispense the combination and monitor for increased side effects of SSRI

D) Dispense the combination and monitor for increased side effects of benzodiazepines

Answer: (d)

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