PEBC (Clinical Sciences) Sample Questions
Categories: PEBC Canada
Ques. All of the following have been implicated in causing toxic nephropathy, EXCEPT:
a. cyclosporine.
b. sulfonamides.
c. cisplatin.
d. penicillamine.
e. erythromycin.
Ques. In the treatment of a patient who has a solid tumour, which of the following side effects typically occurs one to two weeks after chemotherapy?
a. Neuropathy
b. Cardiotoxicity
c. Neutropenia
d. Emesis
e. Nephrotoxicity
Ques. Lactose intolerance is classified as a(n):
a. allergy
b. enzyme deficiency.
c. mineral deficiency.
d. transporter abnormality.
e. vitamin deficiency.
Ques. A community pharmacist conducts a medication review for a 67 year old patient who has a 20-year history of COPD, diabetes and depression. The patient's current medications include the following:
Aclidinium 400 mcg inhaler, one inhalation bid
Budesonide 200 mcg/formoterol 6 mcg Turbuhaler, 2 inhalations bid
Salbutamol 100 mcg MDI, 2 inhalations qid
Sitagliptin 100 mg, one tablet po daily
Metformin 500 mg, one tablet po tid
Venlafaxine ER 150 mg, one capsule po at bedtime
Which of the following drug therapy problems should be identified for this patient?
a. Taking too high a dosage of aclidinium
b. Taking too high a dosage of metformin
c. Inappropriate dosing time for venlafaxine
d. Drug interaction between sitagliptin and metformin
e. Duplication of therapy with salbutamol and formoterol
Ques. Which of the following is characterized as an autoimmune disorder?
a. Alzheimer disease
b. Systemic lupus erythematosus
c. Osteoarthritis
d. Parkinson disease
e. Paget disease
Ques. A pregnant female presents with a prescription for an antibiotic for treatment of a urinary tract infection. She tells the pharmacist that she doesn't know why the doctor gave her the medication, because she isn't experiencing any symptoms. Her presentation is consistent with which of the following diagnoses?
a. Cystitis
b. Septicemia
c. Urinary retention
d. Pyelonephritis
e. Asymptomatic bacteriuria
Ques. A community pharmacist would like to begin a diabetic education program for local patients newly diagnosed with type 2 diabetes mellitus. Beneficial information for this group includes all of the following EXCEPT:
a. strategies to minimize cardiac risk factors.
b. the facts on diabetes and its complications.
c. the role of blood glucose monitoring.
d. appropriate dietary recommendations.
e. the technique for the mixing of insulins.
Ques. Which of the following would be the most appropriate treatment for moderate to severe atopic dermatitis in an 8 year old child?
a. Urea 20% cream
b. Tacrolimus 0.03% cream
c. Pimecrolimus 1% cream
d. Betamethasone dipropionate 0.05% ointment
e. Clobetasone propionate 0.05% cream
In these questions inclusive refer to the following:
TK is a 63 year old male with chronic kidney disease (CrCl = 29 mL/min/1.73m2) and gout. He experienced his last gout attack about two months ago. Today his toe is extremely painful, hot, red, and swollen. At a walk-in clinic, he receives a prescription for naproxen 500 mg po bid for five days. TK's other current medication is pravastatin 20 mg po at bedtime.
Ques. What drug therapy problem should the pharmacist identify for TK?
a. Naproxen is inferior to indomethacin for the treatment of acute gout.
b. The duration of naproxen treatment is too short.
c. Naproxen should be avoided in patients taking pravastatin.
d. Naproxen should be avoided in patients with renal dysfunction.
e. The frequency of naproxen dosing is too low.
Ques. Following successful resolution of the acute episode, TK's physician decides that he should initiate allopurinol. TK should be advised to:
a. limit fluid intake.
b. take medication on an empty stomach.
c. use precautions to avoid photosensitivity.
d. report any skin rash or itching to the physician.
e. avoid dairy products or multivitamins within 2 hours of dose.