PEBC (Neurological Drugs & Respiratory Drugs) Sample Questions Set-4
Categories: PEBC Canada
Question. MD, a 21 year old, presents with a purpuric skin rash. She wonders if she is having another flare-up of her eczema, but this rash looks different. Her patient record is as follows: Allergies: penicillin, History: eczema x 2.5 years, epilepsy x 1 month. Current medications: betamethasone (Betnovate) Cr 0.05% bid prn x 2.5 years, ethinyl estradiol/ levonorgestrel (Min-Ovral) x 10 months. Lamotrigine 75mg daily.
What is the most probable cause of her skin rash?
A. An acute flare-up of her eczema
B. Skin rash is major side effect of lamotrigine
C. A reaction to oral contraceptives
D. An interaction between ethinyl estradiol/ levonorgestrel (Min-Ovral) and phenytoin
Answer. (b)
Question. Which of the following antiepileptic drugs' skin rash effect can trigger when the drugs initially taken high dose?
A) Phenytoin
B) carbamazepine
C) Valproic acid
D) Lamotrigine
E) Topiramate
Answer. (d)
Question. Which of the following side effects of lamotrigine. Patient should be informed to contact the doctor immediately?
a) Liver toxicity
B) Weight gain
C) dizziness
D) skin rash
E) Fever
Answer. (d)
Question. Florence is a 72-year-old patient suffering from acute pneumonia and COPD. He is allergic to penicillin. He is currently taking Aminophylline infusion by i.v. drip at a rate of 40mg/h, ceftazidime 1g IVPB q8h, Gentamicin 100 mg IVPB q12h and albuterol 5% nebulizer solution q4h prn. The culture and sensitivity report for the sputum specimen indicates the following minimum inhibitory concentration (MICs):
Ceftazidime ≤ 8 mcg/ml
Mezlocillin ≤ 8 mcg/ml
Gentamicin = 4 mcg/ml
Tobramycin ≤ 0.5 mcg/ml
Ciprofloxacin = 8 mcg/ml
Based on these results, a rational therapeutic decision would be to:
a. Continue existing regimens without change
b. Continue ceftazidime only
c. Continue gentamicin; change ceftazidime to mezlocillin
d. Change gentamicin to tobramycin; continue ceftazidime
e. Change ceftazidime to mezlocillin; discontinue gentamicin
Answer. (d)
Question. Which is the most common organism for community acquired pneumonia?
A) Streptococcus pneumonia
B) Micoplasma pneumoniae
C) S. aureus
D) E. coli
E) Pseudomonas aeruginosa
Answer. (a)
Question. CS is a 68-yo male who presented to the ER this morning at 0200 hours with a 2-day history of productive cough with fever. He also complained of shortness of breath. He decided to seek medical treatment because the chest pain and other symptoms were preventing restful sleep. It was decided to admit CS to the hospital with a diagnosis of community-acquired pneumonia.
The following antibiotic regimen was ordered:
Ceftriaxone 1 g IV q 12 h and clarithromycin 500 mg po q 12 h.
What comment would you make during rounds this morning regarding the dosing of the antibiotics?
I) The ceftriaxone and clarithromycin doses must be reduced based on CS’s estimated renal function.
II) These antibiotics should be given at least 1 hour apart.
III) Ceftriaxone can be given q 24 h for the treatment of community acquired pneumonia.
A) I only
B) III only
c) I and II only
d) II and III only
e) I, II and III
Answer. (b)
Question. JS is a 78-yo male who was admitted to the hospital yesterday from an area nursing home with fever, chills, vomiting, and severe flank pain. Which of the following would NOT need to be adjusted in a patient with decreased renal function?
A. Ampicillin
B. Ceftazimide
C. Ceftriaxone
D. Ticarcillin and clavulanate potassium
E. Piperacillin and tazobactam
Answer. (c)
Question. Which is the most common organism for community acquired pneumonia?
A. Legionalla pneumoniae
B. Staphulococcus pneuminae
C. Streptococcus pneumoniae
D. H. influenza
E. M. catharrhalis
Answer. (c)
Question. PJK is a 35 year old female. She has been a customer of your pharmacy and brings prescription a new albuterol inhaler, and asks how he can tell if he has doses left in his albuterol inhaler. He says he had a bad asthma attack recently and had plenty of albuterol on hand, but it has crossed his mind that he would be big trouble if his Albuterol inhaler were ever empty? The pharmacist advices patient!
A) Pt the inhaler in water for the "float test"
B) Have extra available, and to be sure to write down the date of his refill to have at least a rough idea of how much of this reliever medication is left
C) Shake inhaler if you hear sound of powder in, there should be sufficient medication
D) If you get dry mist after inhalation that means still there is medication
E) None of the above
Answer. (b)
40) PJK in short-acting beta agonist (SABA) salbutamol inhaler PRN and inhaled corticosteroid budosenide bid for asthma. He has frequent exacerbation and frequently hospitalized due to asthma exacerbation. The doctor prescribed leukotriene inhibitor montelukast. What benefits would the patient experience with new medication?
I) Decreased use of short acting beta agonist
II) Decreased hospitalization
III) Decrease frequent attacks
A) I only
B) III only
C) I and II
D) II and III
E) I, II, III
Answer. (e)