PEBC (Neurological Drugs & Respiratory Drugs) Sample Questions Set-6
Categories: PEBC Canada
Question. KP is a 27 year old man using salbutamol and fluticasone inhalers for asthma. Having a dry cough. He asks the pharmacist, why all OTC cough suppressants like dextromethorphan (DM) should be avoided?
A) DM may hide early symptoms of asthma attack
B) DM interact with corticosteroids making both ineffective
C) All people asthma should consult with physician as soon as respiratory symptoms develops
D) codeine is more safe and effective for people with asthma
Answer. (a)
Question. KK, is a 43-year-old male, presents to your pharmacy requesting something for his “ulcer.” On questioning him, you learn that:
1) he has had “stomach pains: that have been getting progressively worse over the month;
2) he does not take any NSAIDs/ASA;
3) his pain does not rise towards the neck (heartburn);
4) he has not alarm features; and
5) he has never been diagnosed with an ulcer.
He smokes 3 to 4 cigarettes a day and usually has 2 glasses of wine with dinner. Based on the evidence, what would be an appropriate next step to manage KK?
a) Stop the cigarettes and the wine
b) Try an alginate-containing product
c) Suggest he see his family doctor for possible H. pylori testing.
d) Go to the Emergency room to be assessed for a possible peptic ulcer
Answer. (c)
Question. PK is a 58-year-old female with moderate persistent low back pain. She is currently taking acetaminophen 300 mg/codeine 30 mg, 4 to 6 tablets per day and senna, 2 tablets per day for constipation. Her pain score is 6/10. She doesn’t like the inconvenience of taking so many pills and would like to reduce her pill burden. Her physician would like to switch her to a pain patch for more consistent pain control.
Which of the following would be the most appropriate for PK?
I) Buprenorphine transdermal system
II) Fentanyl transdermal system
III) acetaminophen + codeine + caffeine PRN
Answer. (e)
Question. Which of the following is/are appropriate counselling point(s) for transdermal administration of opioids?
I) Advise patients to avoid exposure to external heat sources as they can increase the release of buprenorphine or fentanyl and may result in an overdose.
II) Advise patients to avoid strenuous exercises as they may increase absorption of buprenorphine or fentanyl and may result in an overdose.
III) Advise patients to contact their physician or pharmacist if they develop a high fever as fever can increase release of buprenorphine or fentanyl and may result in an overdose.
Answer. (a)
Question. MP is a 50 year old male participating in your pharmacy cardiovascular risk assessment clinic. He has a history of hypertension or diabetes and has never smoked. He has no recent blood work on file. A fasting lipid panel is ordered to assess his cardiovascular risk. Which of the following lab tests should be completed at baseline in the event the patient is started on a statin?
I) AST/ALT
II) Creatine kinase
III) Electrolytes
Answer. (a)
Question. MP is a 22-year-old woman, otherwise healthy, presents with a 6-month history of episodes of unresponsiveness accompanied by lip smacking lasting 1 to 2 minutes and occurring 2 to 3 times per month. She takes no medications She is in a monogamous relationship with a male sexual partner and only occasionally uses contraception. A routine EEG shows left temporal epileptiform activity and MRI of the brain shows left mesial temporal sclerosis. Which of the following drugs have decreased the effectiveness of oral contraceptive pills?
i. Gabapentin
ii. Lamotrigine
iii. Topiramate
a) I only
b) III only
c) I and II
d) II and III
e) I, II III
Answer. (b)
Question. Which of the following drugs are associated with hirsutism side effects?
A) Phenytoin
B) Carbamazepine
C) valproic acid
D) Topiramate
E) Lamotrigine
Answer. (a)
Question. After her phenytoin therapy has been optimized, MP returns to the clinic just before her wedding and requests an oral contraceptive. Which of the following statements regarding oral contraceptives and phenytoin is most correct?
A. There is no potential drug-drug interaction
B. Phenytoin inhibits the metabolism of phenytoin and may increase their side effects.
C. Oral contraceptives inhibit the metabolism of phenytoin and may increase its side effects.
D. Phenytoin induces the metabolism of oral contraceptives and may decrease their efficacy.
E. Oral contraceptives induce the metabolism of phenytoin and may decrease its efficacy.
Answer. (d)
Question. Doctor doubled dose of phenytoin, when to measure steady state concentration?
A) After 1 day
B) After 1 week
C) After 1 month
D) After 2 week
E) After 3 week
Answer. (b)